The KISS Principle is a design principle that stems from the 1960. It originated in engineering and its view point is that most systems work best if they are kept simple rather than made complicated; therefore, simplicity should be a key goal in design, and unnecessary complexity should be avoided. But what about complex systems such as nature? How simple can we go before oversimplification results in incomplete, or biased data? Before absence of consideration of relevant factors inherently lead to regrettable substitutions? And before we willingly accept that there will be collateral damages to a decision, without knowing (or wanting to know) of what nature and in what order of magnitude these may be? One example that illustrates where this challenge may rear what is its ugly head: upcoming Swiss political referenda on agricultural practices.